The nondigestible fat sucrose polyester does not stimulate gallbladder emptying in humans

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Sucrose polyester does not inhibit gastric acid secretion or stimulate cholecystokinin release in men1-3

Replacement of dietary lilt by sucrose polyester reduces fat intake. However, little is known about the effccts of sucrose polyester on gastrointestinal function. To investigate the effect on gastric acid secretion and on release of cholecystokinin into plasma, we perfused eight healthy male volunteers intraduodenally with sucrose polyester, digestible fat, or saline on separate days in random ...

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Sucrose polyester does not inhibit gastric acid secretion or stimulate cholecystokinin release in men.

Replacement of dietary fat by sucrose polyester reduces fat intake. However, little is known about the effects of sucrose polyester on gastrointestinal function. To investigate the effect on gastric acid secretion and on release of cholecystokinin into plasma, we perfused eight healthy male volunteers intraduodenally with sucrose polyester, digestible fat, or saline on separate days in random o...

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Gastric inhibitory polypeptide does not inhibit gastric emptying in humans.

The insulinotropic gut hormone gastric inhibitory polypeptide (GIP) has been demonstrated to inhibit gastric acid secretion and was proposed to possess "enterogastrone" activity. GIP effects on gastric emptying have not yet been studied. Fifteen healthy male volunteers (23.9 +/- 3.3 yr, body mass index 23.7 +/- 2.3 kg/m(2)) were studied with the intravenous infusion of GIP (2 pmol.kg(-1).min(-1...

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By-passing the sphincter of Oddi does not affect gallbladder emptying in the pig.

A study of the relationship between bile secretion and nutrition in the pig requires a complete and continuous collection of the bile and its reinfusion to the animal. In most of the studies performed in different species, bile has been directly reinfused into the duodenum, leading to the exclusion of the sphincter of Oddi from the biliary pathway. It has been postulated that such an exclusion ...

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Adaptation to high-fat diet accelerates emptying of fat but not carbohydrate test meals in humans.

Previous work has shown that the gastric emptying rate in animals and humans can adapt due to previous dietary intake. The present study investigated whether adaptation in gastric emptying rate due to consumption of a high-fat diet (HFD) is nutrient specific in humans. Gastric emptying of high-fat and high-carbohydrate test meals was measured (using gamma scintigraphy) before and after consumpt...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 1998

ISSN: 0002-9165,1938-3207

DOI: 10.1093/ajcn/68.6.1272